Hemolytic disease of the newborn, also known as hemolytic disease of the fetus and newborn, HDN, HDFN, or erythroblastosis fetalis, is an alloimmune condition that develops in a fetus, when the IgG molecules (one of the five main types of antibodies) produced by the mother pass through the placenta. Among these antibodies are some which attack the red blood cells in the fetal circulation; the red cells are broken down and the fetus can develop reticulocytosis and anemia. This fetal disease ranges from mild to very severe, and fetal death from heart failure (hydrops fetalis) can occur. When the disease is moderate or severe, many erythroblasts are present in the fetal blood and so these forms of the disease can be called erythroblastosis fetalis (or erythroblastosis foetalis).
Read more about Hemolytic Disease Of The Newborn: Symptoms, Causes, Serological Diagnoses, Diagnosis, Treatment, Complications and Similar Conditions, In Animals
Famous quotes containing the words disease and/or newborn:
“His poor self,
A dedicated beggar to the air,
With his disease of all-shunned poverty,
Walks, like contempt, alone.”
—William Shakespeare (1564–1616)
“You’re looking, sir, at a very dull survivor of a very gaudy life. Crippled, paralyzed in both legs. Very little I can eat, and my sleep is so near waking that it’s hardly worth the name. I seem to exist largely on heat, like a newborn spider.”
—William Faulkner (1897–1962)