Combinations With Other Conditions
Individuals with sickle cell–hemoglobin C (HbSC), have the gene for HbS inherited from one parent and the gene for HbC is inherited from the other parent: they are "heterozygous". Since HbC does not polymerize as readily as HbS, there is less sickling (fewer sickle cells). The peripheral smear demonstrates mostly target cells and only a few sickle cells. There are fewer acute vaso-occlusive events. However, persons with hemoglobin SC disease (HbSC) have more significant retinopathy, ischemic necrosis of bone, and priapism than those with pure SS disease.
Read more about this topic: Hemoglobin C
Famous quotes containing the words combinations and/or conditions:
“I had a quick grasp of the secret to sanity—it had become the ability to hold the maximum of impossible combinations in one’s mind.”
—Norman Mailer (b. 1923)
“... we have every reason to rejoice when there are so many gains and when favorable conditions abound on every hand. The end is not yet in sight, but it can not be far away. The road before us is shorter than the road behind.”
—Lucy Stone (1818–1893)