Combinations With Other Conditions
Individuals with sickle cell–hemoglobin C (HbSC), have the gene for HbS inherited from one parent and the gene for HbC is inherited from the other parent: they are "heterozygous". Since HbC does not polymerize as readily as HbS, there is less sickling (fewer sickle cells). The peripheral smear demonstrates mostly target cells and only a few sickle cells. There are fewer acute vaso-occlusive events. However, persons with hemoglobin SC disease (HbSC) have more significant retinopathy, ischemic necrosis of bone, and priapism than those with pure SS disease.
Read more about this topic: Hemoglobin C
Famous quotes containing the words combinations and/or conditions:
“The more elevated a culture, the richer its language. The number of words and their combinations depends directly on a sum of conceptions and ideas; without the latter there can be no understandings, no definitions, and, as a result, no reason to enrich a language.”
—Anton Pavlovich Chekhov (1860–1904)
“Any man who does not accept the conditions of life sells his soul.”
—Charles Baudelaire (1821–1867)