Heifetz is a Jewish surname from Belarus and Lithuania. It derives from Hebrew חפץ (chefets; "delight" "pleasure"). It is also spelled Chafets, Chaffetz, Chaifetz, Chofets. It may refer to:
- Jascha Heifetz, Lithuanian-born violinist
- Danny Heifetz, American musician
- Ronald A. Heifetz, American leadership teacher
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