Heart Murmur - Interventions That Change Murmur Sounds

Interventions That Change Murmur Sounds

  • Inhalation leads to drop in intrathoracic pressure, which increases the capacity of pulmonary circulation, thereby prolonging ejection time. This will affect the closure of the pulmonary valve. This finding, also called Carvallo's maneuver, has been found by studies to have a sensitivity of 100% and a specificity of 80% to 88% in detecting murmurs originating in the right heart. specifically positive Carvallo's sign describes the increase in intensity of a tricuspid regurgitation murmur with inspiration.
  • abrupt standing
  • Squatting, by increasing preload
  • Handgrip maneuver, by increasing afterload
  • Valsalva maneuver. One study found the Valsalva maneuver to have a sensitivity of 65%, specificity of 96% in detecting hypertrophic obstructive cardiomyopathy (HOCM). Both standing and Valsalva maneuver will decrease venous return and subsequently decrease left ventricular filling, resulting in an increase in the loudness of the murmur of hypertrophic cardiomyopathy, since outflow obstruction is increased by decreasing preload. Alternatively, squatting increases venous return and thus decreases the murmur. Maximum handgrip exercise also results in a decreased loudness of the murmur.
  • post ectopic potentiation
  • amyl nitrite
  • methoxamine
  • positioning of the patient. That is, putting patients in the left lateral position will allow a murmur in the mitral valve area to be more pronounced.

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