Endodontic Success and Failure
It is possible that after conventional endodontic therapy has been completed, little to no resolution of the periapical lesion occurs over a considerable amount of time; there is a great deal of current research that discusses the possible reasons for this outcome and suggests possible treatment options. For example, it has been demonstrated that there is an association between nonresolving apical periodontitis lesions and the presence of cholesterol clefts within the periapical lesion; in fact, an incidence of up to 44% has been reported! It was shown that macrophages joined to form multinucleated giant cells and then produced a well-circumscribed area of tissue reaction, not unlike the granulomatous tissue reactions of a typical foreign body reaction, and persisted for up to 8 months. Similarly, endodontic materials as well as food debris may also be the cause of persistent periapical lesions. It was once shown that contaminated gutta percha resulted in a persistent periapical lesion for more than a decade!
Read more about this topic: Healing Of Periapical Lesions
Famous quotes containing the words success and/or failure:
“To burn always with this hard, gemlike flame, to maintain this ecstasy, is success in life.”
—Walter Pater (1839–1894)
“Human beings are compelled to live within a lie, but they can be compelled to do so only because they are in fact capable of living in this way. Therefore not only does the system alienate humanity, but at the same time alienated humanity supports this system as its own involuntary masterplan, as a degenerate image of its own degeneration, as a record of people’s own failure as individuals.”
—Václav Havel (b. 1936)