Endodontic Success and Failure
It is possible that after conventional endodontic therapy has been completed, little to no resolution of the periapical lesion occurs over a considerable amount of time; there is a great deal of current research that discusses the possible reasons for this outcome and suggests possible treatment options. For example, it has been demonstrated that there is an association between nonresolving apical periodontitis lesions and the presence of cholesterol clefts within the periapical lesion; in fact, an incidence of up to 44% has been reported! It was shown that macrophages joined to form multinucleated giant cells and then produced a well-circumscribed area of tissue reaction, not unlike the granulomatous tissue reactions of a typical foreign body reaction, and persisted for up to 8 months. Similarly, endodontic materials as well as food debris may also be the cause of persistent periapical lesions. It was once shown that contaminated gutta percha resulted in a persistent periapical lesion for more than a decade!
Read more about this topic: Healing Of Periapical Lesions
Famous quotes containing the words success and/or failure:
“The best augury of a man’s success in his profession is that he thinks it the finest in the world.”
—George Eliot [Mary Ann (or Marian)
“Parents are never forgiven for not giving just the right response at the appropriate moment. Or, rather, there are particular times in the adolescent’s or young adult’s life, when a certain response is needed, and this need is not met, and the failure to meet this need is forever remembered, and is never forgiven.”
—Terri Apter (20th century)