Headspace may refer to:
- Headspace (Pulse Ultra album), 2002
- Headspace (Ashton Nyte album), 2005
- Headspace (band), a British progressive metal band formed in 2006
- Headspace technology, the gaseous constituents of a closed space above liquids or solid emitting and vapors measured using headspace gas chromatography
- Headspace (firearms), a chamber measurement
- Headspace (organisation), Australian Youth mental health initiative
- Headspace (film), a 2005 horror film
- Headspace or ullage, the unfilled space in a container