Harrison's Principles of Internal Medicine is an American textbook of internal medicine. First published in 1950, it is presently in its eighteenth edition (published in July 2011 by McGraw-Hill). Although it is aimed at all members of the medical profession, it is mainly used by internists and junior doctors in this field, as well as medical students. It has been described as the "most recognized book in all of medicine."
The work is named after Tinsley R. Harrison of Birmingham, Alabama, who served as editor-in-chief of the first five editions and established the format of the work: a strong basis of clinical medicine interwoven with an understanding of pathophysiology.
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