Hambone may refer to:
- Literally, the bone found in ham meat
- Hambone (magazine), a literary magazine
- Juba dance, a style of dance that involves stomping as well as slapping and patting the arms, legs, chest, and cheeks
- Hambone Willie Newbern (1899–1947), a guitar-playing blues musician
- "Hambone", a song by Red Saunders (musician)