Haldane's rule represents a fundamental observation in early mechanisms of the process of speciation. It was formulated in 1922 by the British evolutionary biologist J.B.S. Haldane:
"When in the F1 offspring of two different animal races one sex is absent, rare, or sterile, that sex is the heterozygous sex ."Read more about Haldane's Rule: Description, Hypotheses, Exceptions
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