Course
The Guyandotte River is formed in southwestern Raleigh County by the confluence of three streams, Winding Gulf, Stonecoal Creek, and the Devils Fork. and flows initially west-northwestwardly into Wyoming and Mingo counties. It turns briefly northward in Mingo County and enters Logan County, where it turns north-northwestwardly for the remainder of its highly meandering course through Logan, Lincoln and Cabell counties. It enters the Ohio River from the south at Huntington, about 5 mi (8 km) east of the city's downtown.
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