Groesbeck, as a person, may refer to:
- Alex J. Groesbeck (1873–1953), American governor of Michigan (1921-1927)
- Robert A. Groesbeck, American mayor of Henderson, Nevada (1993-1997)
- William S. Groesbeck (1815–1897), American U.S. Representative of Ohio
Groesbeck, as a place, may refer to:
- Groesbeck, Ohio, an unincorporated census-designated place in Hamilton County, Ohio, United States
- Groesbeck, Texas, a city in Limestone County, Texas, United States