Granulocyte Macrophage Colony-stimulating Factor
| Gene Ontology | |
|---|---|
| Molecular function | • cytokine activity • granulocyte macrophage colony-stimulating factor receptor binding • protein binding • growth factor activity |
| Cellular component | • extracellular region • extracellular space |
| Biological process | • embryonic placenta development • immune response • positive regulation of cell proliferation • positive regulation of gene expression • positive regulation of macrophage derived foam cell differentiation • positive regulation of interleukin-23 production • epithelial fluid transport • positive regulation of tyrosine phosphorylation of Stat5 protein • myeloid dendritic cell differentiation • negative regulation of apoptotic process • positive regulation of DNA replication • positive regulation of survival gene product expression • negative regulation of cytolysis • positive regulation of podosome assembly • dendritic cell differentiation |
| Sources: Amigo / QuickGO | |
131.41 – 131.41 Mb
54.25 – 54.25 Mb
| Granulocyte-macrophage colony-stimulating factor | |||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor | |||||||||||||||||||||||||||||||||||||
| Identifiers | |||||||||||||||||||||||||||||||||||||
| Symbol | GM_CSF | ||||||||||||||||||||||||||||||||||||
| Pfam | PF01109 | ||||||||||||||||||||||||||||||||||||
| Pfam clan | CL0053 | ||||||||||||||||||||||||||||||||||||
| InterPro | IPR000773 | ||||||||||||||||||||||||||||||||||||
| PROSITE | PDOC00584 | ||||||||||||||||||||||||||||||||||||
| SCOP | 2gmf | ||||||||||||||||||||||||||||||||||||
| SUPERFAMILY | 2gmf | ||||||||||||||||||||||||||||||||||||
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a protein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts. Read more about Granulocyte Macrophage Colony-stimulating Factor: Functions, Genetics, Glycosylation, Clinical Significance Famous quotes containing the word factor:“It is change, continuing change, inevitable change, that is the dominant factor in society today. No sensible decision can be made any longer without taking into account not only the world as it is, but the world as it will be.... This, in turn, means that our statesmen, our businessmen, our everyman must take on a science fictional way of thinking.” | |||||||||||||||||||||||||||||||||||||