GPB may refer to:

  • Georgia Public Broadcasting, the public broadcast network in the state of Georgia
  • Georgian Public Broadcaster, the national public broadcaster of the nation of Georgia
  • Global power barometer, a system which tracks global trends
  • Gravity Probe B (or GP-B), a satellite mission to study the relativistic effects of Earth's gravity
  • Google Protocol Buffers, protocol buffers are a method of serializing structured data