Glyoxylic Acid - Preparation

Preparation

The compound is formed by organic oxidation of glyoxal with hot nitric acid, the main side product being oxalic acid. Ozonolysis of maleic acid is also effective.

The conjugate base of gloxylic acid is known as glyoxylate and is the form that the compound exists in solution at neutral pH. Glyoxylate is an intermediate of the glyoxylate cycle, which enables organisms, such as bacteria, fungi, and plants to convert fatty acids into carbohydrates. Glyoxylate is the byproduct of the amidation process in biosynthesis of several amidated peptides.

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