Glycogen Phosphorylase - Historical Significance

Historical Significance

Glycogen phosphorylase was the first allosteric enzyme to be discovered. This accomplishment was one of many landmark achievements made by Carl and Gerty Cori. In 1943, with the help of Arda Green, the pair illustrated that glycogen phosphorylase existed in either the a or b forms depending on its phosphorylation state, as well as in the R or T states based on the presences of AMP.

Read more about this topic:  Glycogen Phosphorylase

Famous quotes containing the words historical and/or significance:

    What is the historical function of Parliament in this country? It is to prevent the Government from governing.
    George Bernard Shaw (1856–1950)

    History is the interpretation of the significance that the past has for us.
    Johan Huizinga (1872–1945)