Historical Significance
Glycogen phosphorylase was the first allosteric enzyme to be discovered. This accomplishment was one of many landmark achievements made by Carl and Gerty Cori. In 1943, with the help of Arda Green, the pair illustrated that glycogen phosphorylase existed in either the a or b forms depending on its phosphorylation state, as well as in the R or T states based on the presences of AMP.
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“Religion means goal and way, politics implies end and means. The political end is recognizable by the fact that it may be attained—in success—and its attainment is historically recorded. The religious goal remains, even in man’s highest experiences, that which simply provides direction on the mortal way; it never enters into historical consummation.”
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“I am not afraid that I shall exaggerate the value and significance of life, but that I shall not be up to the occasion which it is.”
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