Glycine-t RNA Ligase

Glycine-t RNA Ligase

Identifiers Symbols GARS; CMT2D; DSMAV; GlyRS; HMN5; SMAD1 External IDs OMIM: 600287 MGI: 2449057 HomoloGene: 1547 GeneCards: GARS Gene EC number 6.1.1.14

Gene Ontology
Molecular function	• glycine-tRNA ligase activity • ATP binding • protein dimerization activity
Cellular component	• cytoplasm • mitochondrial matrix • cytosol • secretory granule
Biological process	• tRNA aminoacylation for protein translation • glycyl-tRNA aminoacylation • cell death • gene expression • diadenosine tetraphosphate biosynthetic process
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2617 353172 Ensembl ENSG00000106105 ENSMUSG00000029777 UniProt P41250 Q9CZD3 RefSeq (mRNA) NM_002047 NM_180678 RefSeq (protein) NP_002038 NP_851009 Location (UCSC) Chr 7:
30.63 – 30.67 Mb Chr 6:
55.04 – 55.08 Mb PubMed search

Glycine—tRNA ligase also known as glycyl-tRNA synthetase is an enzyme that in humans is encoded by the GARS gene.