Structure
| Glutathione S-transferase, C-terminal domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Structure of the xenobiotic substrate binding site of rat glutathione S-transferase mu 1 bound to the GSH adduct of phenanthrene-9,10-oxide. | |||||||||
| Identifiers | |||||||||
| Symbol | GST_C | ||||||||
| Pfam | PF00043 | ||||||||
| InterPro | IPR004046 | ||||||||
| SCOP | 2gst | ||||||||
| SUPERFAMILY | 2gst | ||||||||
| CDD | cd00299 | ||||||||
|
|||||||||
Mammalian cytosolic GSTs are dimeric both subunits being from the same class of GSTs, although not necessarily identical. The monomers are in the range of 22–30 kDa. They are active over a wide variety of substrates with considerable overlap.
Read more about this topic: Glutathione S-transferase
Famous quotes containing the word structure:
“One theme links together these new proposals for family policy—the idea that the family is exceedingly durable. Changes in structure and function and individual roles are not to be confused with the collapse of the family. Families remain more important in the lives of children than other institutions. Family ties are stronger and more vital than many of us imagine in the perennial atmosphere of crisis surrounding the subject.”
—Joseph Featherstone (20th century)
“What is the most rigorous law of our being? Growth. No smallest atom of our moral, mental, or physical structure can stand still a year. It grows—it must grow; nothing can prevent it.”
—Mark Twain [Samuel Langhorne Clemens] (1835–1910)
“There is no such thing as a language, not if a language is anything like what many philosophers and linguists have supposed. There is therefore no such thing to be learned, mastered, or born with. We must give up the idea of a clearly defined shared structure which language-users acquire and then apply to cases.”
—Donald Davidson (b. 1917)