Glucose Transporter - Synthesis of Free Glucose

Synthesis of Free Glucose

Most non-autotrophic cells are unable to produce free glucose because they lack expression of glucose-6-phosphatase and, thus, are involved only in glucose uptake and catabolism. Usually only produced in hepatocytes, in fasting conditions other tissues such as the intestines, muscles, brain and kidneys are able to produce glucose following activation of gluconeogenesis.

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