Glucose Transport in Yeast
In Saccharomyces cerevisiae glucose transport takes place through facilitated diffusion. The transport proteins are mainly from the Hxt family, but many other transporters have been identified.
| Name | Properties | Notes |
| Snf3 | low-glucose sensor; repressed by glucose; low expression level; repressor of Hxt6 | |
| Rgt2 | high-glucose sensor; low expression level | |
| Hxt1 | Km: 100 mM, 129 - 107 mM | low-affinity glucose transporter; induced by high glucose level |
| Hxt2 | Km = 1.5 - 10 mM | high/intermediate-affinityglucose transporter; induced by low glucose level |
| Hxt3 | Vm = 18.5, Kd = 0.078, Km = 28.6/34.2 - 60 mM | low-affinity glucose transporter |
| Hxt4 | Vm = 12.0, Kd = 0.049, Km = 6.2 | intermediate-affinity glucose transporter |
| Hxt5 | Km = 10 mM | Moderate glucose affinity. Abundant during stationary phase, sporulation and low glucose conditions. Transcription repressed by glucose. |
| Hxt6 | Vm = 11.4, Kd = 0.029, Km = 0.9/14, 1.5 mM | high glucose affinity |
| Hxt7 | Vm = 11.7, Kd = 0.039, Km = 1.3, 1.9, 1.5 mM | high glucose affinity |
| Hxt8 | low expression level | |
| Hxt9 | involved in pleiotropic drug resistance | |
| Hxt11 | involved in pleiotropic drug resistance | |
| Gal2 | Vm = 17.5, Kd = 0.043, Km = 1.5, 1.6 | high galactose affinity |
Read more about this topic: Glucose Transporter
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