Glucosamine - Preliminary Research

Preliminary Research

If glucosamine sulfate actually is proven to be effective in patients with osteoarthritis, it may result from anti-inflammatory activity, stimulation of proteoglycan synthesis, decrease in catabolic activity of chondrocytes inhibiting the synthesis of proteolytic enzymes and other substances that contribute to cartilage integrity, or have no effect at all.

As a substrate of the GAG matrix, glucosamine is postulated to stimulate synovial production of hyaluronic acid or possibly to inhibit liposomal enzymes.

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