Glasco, as a person, may refer to:
- Kimberley Glasco (b. 1960), a Canadian ballerina
- Joseph Glasco (1925-1996), an American painter
Glasco, as a place, may refer to:
- Glasco, Kansas, a city in Cloud County, Kansas, United States
- Glasco, New York, a hamlet in Ulster County, New York, United States