Gestational Trophoblastic Disease - Risk Factors

Risk Factors

Two main risk factors increase the likelihood for the development of GTD: 1) The woman being under 20 years of age, or over 35 years of age, and 2) previous GTD.

Although molar pregnancies affect women of all ages, women under 16 years of age have a six times higher risk of developing a molar pregnancy than those aged 16–40 years, and women 50 years of age or older have a one in three chance of having a molar pregnancy.

Being from Asia/of Asian ethnicity is an important risk factor.

The ABO blood groups of the parents appear to be a factor in choriocarcinoma development, i.e. women with blood group A have been shown to have a greater risk than blood group O women.

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