Research
Following his graduation from Cornell, George under- took graduate studies in the genetics of T-even coliphage with S. E. Luria in the Bacteriology Department of the University of Illinois. His studies revealed phenotypic mixing, in which a phage with a host-range genotype of one phage type was found in a particle who was phenotypically dissimilar. When published in 1956, these studies had profound impact on the study of viral biology. During his postdoc at CalTech, with Jean Weigle, he undertook further studies on T2 × T4 hybrids, which led to the discovery of DNA modification (by glucosylation). At the University of Oregon, Streisinger pioneered the study of zebrafish in his lab. Zebrafish can be genetically modified easily, and researchers can modify them to mimic the traits of certain diseases. In analyzing these created diseases, scientists seek solutions to diseases which affect humans. Over 5,000 researchers in 450 labs throughout 31 countries study zebrafish, and many of them received their initial training at the University of Oregon.
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