Genome Research is a peer-reviewed scientific journal published by Cold Spring Harbor Laboratory Press. The focus of the journal is on genome-wide studies in any organism, including single gene studies that are placed in a genomic context. This scope includes both experimental and computational analysis. The journal was established in 1991 as PCR Methods and Applications and obtained its current title in 1995. According to the Journal Citation Reports, the journal has a 2011 impact factor of 13.608.