The Machine Theory
Weismann believed that the initial division of the egg into two cells causes determinants to be divided into two groups, such that one cell will develop, say, the left half of the embryo, while the other cell will generate the right half. With each subsequent division, determinants continue to be meted out differently to different cells until the stage is reached where each cell type is in place. At this point the distinct set of determinants in each cell type produce the developmental machinery that will generate the tissue, organ or system associated with that type of cell.
Weismann’s developmental concept was based on a mistaken interpretation of an 1882 experiment carried about by Wilhelm Roux, in which Roux killed one of the cells of a frog embryo at the two-cell stage. The remaining cell then led to half an embryo, leading Weismann to believe that the determinants for the embryo were divided along with each cell division. As Hans Driesch and other researchers discovered, when the dead cell is removed, the other cell produces a whole organism, not half. It's now well known that all the cells in a given organism contain the same set of genes.
Read more about this topic: Genetic Determinism
Famous quotes containing the words machine and/or theory:
“The white man regards the universe as a gigantic machine hurtling through time and space to its final destruction: individuals in it are but tiny organisms with private lives that lead to private deaths: personal power, success and fame are the absolute measures of values, the things to live for. This outlook on life divides the universe into a host of individual little entities which cannot help being in constant conflict thereby hastening the approach of the hour of their final destruction.”
—Policy statement, 1944, of the Youth League of the African National Congress. pt. 2, ch. 4, Fatima Meer, Higher than Hope (1988)
“The weakness of the man who, when his theory works out into a flagrant contradiction of the facts, concludes So much the worse for the facts: let them be altered, instead of So much the worse for my theory.”
—George Bernard Shaw (18561950)