General Transcription Factor - Types

Types

In bacteria, transcription initiation requires an RNA polymerase and a single GTF: sigma factor.

In archaea and eukaryotes, transcription initiation requires an RNA polymerase and a set of multiple GTFs. The Transcription initiation by eukaryotic RNA polymerase II involves the following GTFs:

  • TFIIA
  • TFIIB
  • TFIID
  • TFIIE
  • TFIIF
  • TFIIH

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