Gaussian Network Model Theory
The Gaussian network model was first proposed in 1996 by Tirion at the atomic level and then one year later reconsidered at the amino-acid level by Bahar, Atilgan, Haliloglu and Erman. The model was influenced by work of PJ Flory on polymer networks and other works that utilized normal mode analysis and simplified harmonic potentials to study dynamics of proteins.
Read more about this topic: Gaussian Network Model
Famous quotes containing the words network, model and/or theory:
“Of what use, however, is a general certainty that an insect will not walk with his head hindmost, when what you need to know is the play of inward stimulus that sends him hither and thither in a network of possible paths?”
—George Eliot [Mary Ann (or Marian)
“The Battle of Waterloo is a work of art with tension and drama with its unceasing change from hope to fear and back again, change which suddenly dissolves into a moment of extreme catastrophe, a model tragedy because the fate of Europe was determined within this individual fate.”
—Stefan Zweig (18811942)
“The weakness of the man who, when his theory works out into a flagrant contradiction of the facts, concludes “So much the worse for the facts: let them be altered,” instead of “So much the worse for my theory.””
—George Bernard Shaw (1856–1950)