Gaussian Network Model Theory
The Gaussian network model was first proposed in 1996 by Tirion at the atomic level and then one year later reconsidered at the amino-acid level by Bahar, Atilgan, Haliloglu and Erman. The model was influenced by work of PJ Flory on polymer networks and other works that utilized normal mode analysis and simplified harmonic potentials to study dynamics of proteins.
Read more about this topic: Gaussian Network Model
Famous quotes containing the words network, model and/or theory:
“Of what use, however, is a general certainty that an insect will not walk with his head hindmost, when what you need to know is the play of inward stimulus that sends him hither and thither in a network of possible paths?”
—George Eliot [Mary Ann (or Marian)
“She represents the unavowed aspiration of the male human being, his potential infidelity—and infidelity of a very special kind, which would lead him to the opposite of his wife, to the “woman of wax” whom he could model at will, make and unmake in any way he wished, even unto death.”
—Marguerite Duras (b. 1914)
“Hygiene is the corruption of medicine by morality. It is impossible to find a hygienest who does not debase his theory of the healthful with a theory of the virtuous.... The true aim of medicine is not to make men virtuous; it is to safeguard and rescue them from the consequences of their vices.”
—H.L. (Henry Lewis)