Gatsby may refer to:
- The Great Gatsby, a 1925 novel by F. Scott Fitzgerald and many adaptations thereof, and its central character Jay Gatsby
- The Late Gatsby - a mashup of The Great Gatsby and a vampire story.
- Gatsby Charitable Foundation, a grant-making trust based in London
- GATSBY, a Japanese cosmetic brand by Mandom, well known for its 'Moving Rubber' range of hair wax
- Gatsby (sandwich), a South African food mainly popular in Cape Town, comes in the form of a long roll with fillings of anything ranging from polony to chicken or steak and hot chips
- Gatsby cap, a hat with a stiff front brim, overlaid with a round body
- Gatsbys American Dream, a progressive rock rock band from Seattle, Washington