Structure
The molecule contains three domains: the C-finger, the N-finger, and the Activation Domain. The C-finger, named for being near the C-terminal, has a Zinc finger DNA binding domain. The N-finger, named for being near the N-terminal also binds DNA and a cofactor named FOG1 (friend of GATA). The Activation Domain is responsible for GATA1's strong transcriptional activation. The gene for GATA1 is on the X-chromosome.
Read more about this topic: GATA1
Famous quotes containing the word structure:
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