Clinical Significance
Gastric lipase can partially compensate for the decrease in production of pancreatic lipase associated with pancreatic dysfunction, giving some means for the body to digest lipids. A limitation of acidic lipases is that they remove only one fatty acid from each triacylglycerol. The free fatty acid can readily cross the epithelial membrane lining the gastrointestinal tract, but the diacylglycerol cannot be transported across. This leaves the acidic lipases less efficient than alkaline lipases.
Read more about this topic: Gastric Lipase
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