Restrictions
The U.S. Food and Drug Administration (FDA) warns to be aware of the potential of foreign packages, which may come from gang printing at the package supplier. Pharmaceutical labels and packaging materials are higher in cost primarily as a result of the additional costs in manufacturing due to segregation, traceability, and security requirements. You cannot gang run pharmaceutical labels that require strict line clearance between label kinds, unless the labeling from gang-printed sheets is adequately differentiated by size, shape, or color (21 CFR Part 211.122f).
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