Gallium 67 Scan - Mechanism

Mechanism

The body generally handles Ga3+ as though it were ferric iron (Fe-III), and thus the free isotope ion is bound (and concentrates) in areas of inflammation, such as an infection site, and also areas of rapid cell division. Gallium (III) (Ga+3) binds to transferrin, leukocyte lactoferrin, bacterial siderophores, inflammatory proteins, and cell-membranes in neutrophils, both living and dead.

This relatively nonspecific gallium binding allows sites with tumor, inflammation, and both acute and chronic infection to be imaged by nuclear scan techniques.

Read more about this topic:  Gallium 67 Scan

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