Gallbladder - Microscopic Anatomy

Microscopic Anatomy

The different layers of the gallbladder are as follows:

  • The epithelium, a thin sheet of cells closest to the inside of the gallbladder
  • The lamina propria, a thin layer of loose connective tissue (the epithelium plus the lamina propria form the mucosa)
  • The muscularis, a layer of smooth muscular tissue that helps the gallbladder contract, squirting its bile into the bile duct
  • The perimuscular ("around the muscle") fibrous tissue, another layer of connective tissue
  • The serosa, the outer covering of the gallbladder that comes from the peritoneum, which is the lining of the abdominal cavity

Unlike elsewhere in the intestinal tract, the gallbladder does not have a muscularis mucosae.

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