GAL4/UAS System

GAL4/UAS System

The GAL4-UAS system is a biochemical method used to study gene expression and function in organisms such as the fruit fly. It was developed by Andrea Brand and Norbert Perrimon in 1993 and is considered a powerful technique for studying the expression of genes. The system has two parts: the GAL4 gene, encoding the yeast transcription activator protein Gal4, and the UAS (Upstream Activation Sequence), an enhancer to which Gal4 specifically binds to activate gene transcription.

Read more about GAL4/UAS System:  Overview, Operation, Extensions

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