Gabriel Synthesis - Alternative Gabriel Reagents

Alternative Gabriel Reagents

Many alternative reagents have been developed to complement the use of phthalimides. Most such reagents, e.g. the sodium salt of saccharin, are electronically similar to the phthalimide salts. In terms of their advantages, some such alternative reagents hydrolyze more readily, extend the reactivity to secondary alkyl halides, and allow the production of secondary amines.

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