Epidemiology and Disease Associations
Fundic gland polyps are found in 0.8 to 1.9% of patients who undergo esophagogastroduodenoscopy, and are more common in middle aged women.
The most important consideration in evaluating patients with fundic gland polyps is determining whether there is an underlying congenital cause for the condition, or whether the condition was acquired. This is to ascertain the risk of development of gastric cancer, and to ascertain the risk of concomitant colon cancer.
Fundic gland polyps can be found in association with the following genetic conditions :
- familial adenomatous polyposis
- attenuated familial adenomatous polyposis syndromes
The following are acquired causes for fundic gland polyps :
- chronic use of proton pump inhibitors (proposed by some authors, denied by others)
- Zollinger-Ellison syndrome
Helicobacter pylori infection does not correlate with fundic gland polyposis, and may cause polyp regression.
Read more about this topic: Fundic Gland Polyposis
Famous quotes containing the words disease and/or associations:
“And this disease that was Swann’s love had so multiplied, it was so intimately tied to all of Swann’s habits, to all his acts, to his thoughts, to his health, to his sleep, to his life, even to what he desired for his afterlife, his love was so much a part of him that it could not be extracted from him without destroying him entirely: as is said in surgery, his love was inoperable.”
—Marcel Proust (1871–1922)
“There is ... no glamor at banquets—I mean the large formal banquets of big associations and societies. There is only a kind of dignified confusion that gradually unhinges the mind.”
—James Thurber (1894–1961)