Limits
In all instances only esters can be used with stable acyl components that can withstand the harsh conditions of the Fries rearrangement. If the aromatic or the acyl component is heavily substituted then the chemical yield will drop due to steric constraints. Deactivating meta-directing groups on the benzene group will also have an adverse effect as can be expected for a Friedel–Crafts acylation.
Read more about this topic: Fries Rearrangement
Famous quotes containing the word limits:
“Europe has what we do not have yet, a sense of the mysterious and inexorable limits of life, a sense, in a word, of tragedy. And we have what they sorely need: a sense of life’s possibilities.”
—James Baldwin (1924–1987)
“Caring for children is a dance between setting appropriate limits as caretakers and avoiding unnecessary power struggles that result in unhappiness.”
—Charlotte Davis Kasl (20th century)
“The limits of my language mean the limits of my world.”
—Ludwig Wittgenstein (1889–1951)