Issue
- Frederick William III of Prussia (1770–1840) married Louise of Mecklenburg-Strelitz and had issue.
- Princess Christine (1772–1773)
- Prince Louis (1773–1796) married Frederica of Mecklenburg-Strelitz and had issue.
- Princess Wilhelmina (1774–1837) married William I of the Netherlands and had issue.
- stillborn son (1777)
- Princess Augusta of Prussia (1780–1841), wife of William II, Elector of Hesse
- Prince Henry of Prussia (1781–1846)
- Prince William (1783–1851) married Marianne of Hesse-Homburg and had issue.
Read more about this topic: Frederika Louisa Of Hesse-Darmstadt
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