Activity
FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body.
- In both males and females, FSH stimulates the maturation of germ cells.
- In males, FSH induces Sertoli cells to secrete inhibin and stimulates the formation of sertoli-sertoli tight junctions (zonula occludens).
- In females, FSH initiates follicular growth, specifically affecting granulosa cells. With the concomitant rise in inhibin B, FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase, there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle.
Like its partner LH, FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone (GnRH). Those pulses, in turn, are subject to the oestrogen feed-back from the gonads.
Read more about this topic: Follicle-stimulating Hormone
Famous quotes containing the word activity:
“The animal is one with its life activity. It does not distinguish the activity from itself. It is its activity. But man makes his life activity itself an object of his will and consciousness. He has a conscious life activity. It is not a determination with which he is completely identified.”
—Karl Marx (1818–1883)
“Moderation is the feebleness and sloth of the soul, whereas ambition is the warmth and activity of it.”
—François, Duc De La Rochefoucauld (1613–1680)
“For art to exist, for any sort of aesthetic activity or perception to exist, a certain physiological precondition is indispensable: rapture.”
—Friedrich Nietzsche (1844–1900)