FMR1 Gene Expression
The FMR1 gene is located on the X chromosome and contains a DNA segment called CGG trinucleotide. In most people, the CGG segment is repeated in the gene approximately 5-44 times. Increased expression of the CGG segment on the FMR1 gene is associated with impaired cognitive and reproductive function. If a person has 45-54 repeats this is considered the “gray zone” or borderline risk, 55-200 repeats is called premutation and more than 200 repeats is considered a full mutation of the FMR1 gene according to the American College of Medical Genetics.
The FMR1 gene can be found on the long (q) arm of the X chromosome at position 27.3, from base pair 146,699,054 to base pair 146,738,156.
Read more about this topic: FMR1
Famous quotes containing the word expression:
“As a man has no right to kill one of his children if it is diseased or insane, so a man who has made the gradual and conscious expression of his personality in literature the aim of his life, has no right to suppress himself any carefully considered work which seemed good enough when it was written. Suppression, if it is deserved, will come rapidly enough from the same causes that suppress the unworthy members of a man’s family.”
—J.M. (John Millington)