Fever of Unknown Origin - Definition

Definition

In 1961 Petersdorf and Beeson suggested the following criteria:

  • Fever higher than 38.3°C (101°F) on several occasions
  • Persisting without diagnosis for at least 3 weeks
  • At least 1 week's investigation in hospital

A new definition which includes the outpatient setting (which reflects current medical practice) is broader, stipulating:

  • 3 outpatient visits or
  • 3 days in the hospital without elucidation of a cause or
  • 1 week of "intelligent and invasive" ambulatory investigation.


Presently FUO cases are codified in four subclasses.

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