Fetal Circulation - at Birth

At Birth

At birth, when the infant breathes for the first time, there is a decrease in the resistance in the pulmonary vasculature, which causes the pressure in the left atrium to increase relative to the pressure in the right atrium. This leads to the closure of the foramen ovale, which is then referred to as the fossa ovalis. Additionally, the increase in the concentration of oxygen in the blood leads to a decrease in prostaglandins, causing closure of the ductus arteriosus. These closures prevent blood from bypassing pulmonary circulation, and therefore allow the neonate's blood to become oxygenated in the newly operational lungs.

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Famous quotes containing the word birth:

    Spirit enters flesh
    And for all it’s worth
    Charges into earth
    In birth after birth
    Ever fresh and fresh.
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    My demon,
    too often undressed,
    too often a crucifix I bring forth,
    too often a dead daisy I give water to
    too often the child I give birth to
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    Anne Sexton (1928–1974)