Clinical Manifestations
Acute, tender, erythematous plaques, nodes, pseudovesicles and, occasionally, blisters with an annular or arciform pattern occur on the head, neck, legs, and arms, particularly the back of the hands and fingers. The trunk is rarely involved. Fever (50%); arthralgia or arthritis (62%); eye involvement, most frequently conjunctivitis or iridocyclitis (38%); and oral aphthae (13%) are associated features.
Differential diagnosis includes erythema multiforme, erythema nodosum, adverse drug reaction, and urticaria. Recurrences are common and affect up to one third of patients.
Read more about this topic: Febrile Neutrophilic Dermatosis