Fannie may refer to:
- Fannie Barrier Williams (1855–1944), an African American educator, political and women's rights activist
- Fannie Barrios, a professional bodybuilder from Venezuela
- Fannie Bloomfield Zeisler (1863–1927), an Austrian-born American pianist
- Fannie C. Williams (1882–1980), an American educator
- Fannie E. Motley, an American schoolteacher and president of the National Association of Teachers in Colored Schools
- Fannie Farmer (1857–1915), an American culinary expert and author
- Fannie Fern Andrews (1867–1950), an American lecturer, teacher, social worker and writer
- Fannie Flagg (born 1944), an American actress, comedienne and author
- Fannie Greenberg (1895–2007), an American supercentenarian
- Fannie Heaslip Lea (1884–1955), an American author and poet
- Fannie Hillsmith (1911–2007), an American cubist painter
- Fannie Hurst (1885–1968), an American novelist
- Fannie Kauffman (1924–2009), a Mexican comedian and actress
- Fannie Lee Chaney (1921–2007), an American baker turned civil rights activist
- Fannie Lou Hamer (1917–1977), an American voting rights activist
- Fannie Nampeyo (1900–1987), a modern and contemporary fine arts potter
- Fannie Pearson Hardy Eckstorm (1865–1946), an American writer, ornithologist and folklorist
- Fannie Porter (1873-c.1940), a well known madam of the 19th century
- Fannie Salter (1883–1966), an American lighthouse keeper noted for her tenure at Turkey Point Light in Maryland
- Fannie Sellins (1872–1919), an American union organizer
- Fannie Ward (1872–1952), a vaudeville and silent film actress