Exenatide - Indications

Indications

  • As an adjunctive therapy, exenatide is indicated to improve glycemic control in patients with type 2 diabetes who are taking metformin, a sulfonylurea, thiazolidinediones, or a combination of metformin and sulfonylurea or thiazolidinediones, but who have not been able to achieve adequate control of blood glucose.
  • Its use with insulin, meglitinides, and alpha-glucosidase inhibitors has not been studied.
  • Some physicians are using exenatide as primary monotherapy, an indication approved by the FDA October 30, 2009 as announced by Eli Lilly and Co.

Note: Since the major action of this drug is to enhance the release of endogenous insulin from the pancreas, exenatide is not for use in type 1 diabetes.

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