Toxicity
The roots, stems, and leaves of the plant are known to be toxic. These parts of the plant contain euphorbol (a complex terpene) and other diterpene esters. These are also known carcinogens. The plant's leaves and stems also contain beta-sitosterol, cycloartenone, octacosanol, and oxime, all of which have known medicinal as well as toxic properties.
Even minor amounts (a few drops) of the juice of the Euphorbia tithymaloides root can irritate mucosal membranes. When ingested, the irritation of the mucosal membranes of the stomach and intestines will cause nausea and vomiting. Topical application causes skin irritation, inflammation, and even blisters. If introduced topically to the eye, severe pain, keratoconjunctivitis, and reduced visual actuity occur. Ingesting even a few seeds can cause violent and persistent vomiting and extreme diarrhea.
If latex or root juice gets on the skin, the victim should immediately wash with soap and warm water. If latex or juice gets in the eye, continuous rinsing with fresh water should be the first course of action. Topical steroids are indicated for skin or eye contact. Intravenous fluids are often administered to counteract the fluid loss due to vomiting and diarrhea.
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