Adverse Effects
As a diuretic, etacrynic acid can cause frequent urination, but this usually resolves after taking the drug for a few weeks.
Etacrynic acid can also cause low potassium levels, which may manifest as muscle cramps or weakness. It has also been known to cause reversible or permanent hearing loss (ototoxicity) and liver damage. On oral administration, it produces diarrhea; intestinal bleeding may occur at higher doses.
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