Structure
The estrogen receptor (ESR) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability.
Read more about this topic: Estrogen Receptor Alpha
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“Who says that fictions only and false hair
Become a verse? Is there in truth no beauty?
Is all good structure in a winding stair?
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—George Herbert (1593–1633)
“A structure becomes architectural, and not sculptural, when its elements no longer have their justification in nature.”
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—Friedrich Dürrenmatt (1921–1990)