Relation To C-reactive Protein
C-reactive protein is an acute phase protein produced by the liver during an inflammatory reaction. Since C-reactive protein levels in the blood rise more quickly after the inflammatory or infective process begins, ESR is often replaced with C-reactive protein measurement. There are specific drawbacks, however: for example, both tests for ESR and CRP were found to be independently associated with a diagnosis of acute maxillary sinusitis so in some cases the combination of the two measurements may improve diagnostic sensitivity and specificity.
Read more about this topic: Erythrocyte Sedimentation Rate
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