Equus ( /ˈeɪkwəs/ or /ˈɛkwəs/; Latin for horse or steed) may refer to:
- Equus (genus), a genus of animals including horses, donkeys, zebras and onagers
- Equus (play), a play by Peter Shaffer
- Equus (film), a film adaptation of the Peter Shaffer play
- Equus (magazine), American monthly lifestyle magazine for horse enthusiasts
- Equus (language), the body language expressed by horses; coined by Monty Roberts
- Equus (comics), a comic book character; an opponent of Superman
- Equus Computer Systems, a computer manufacturer and integrator based in Minnetonka, Minnesota
- Hyundai Equus, Korean automobile model built by Hyundai Motor Company
- "Equus" (piece), a composition for concert band by Eric Whitacre
- "Equus" (song), a song by Blonde Redhead
- "Equus" (song), a song by the Cherry Poppin' Daddies off their 1994 album Rapid City Muscle Car